UFC 303 Predictions, Picks & Betting Odds Tonight ft. Pereira vs Prochazka: Brian Ortega continues to climb the Featherweight Division

Sep 25, 2021; Las Vegas, Nevada, USA; Brian Ortega moves in for a hit against Alexander Volkanovski during UFC 266 at T-Mobile Arena.
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Matthew Lowrimore

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Matthew has been with Pickswise for a while now, covering a wide variety of sports. His main passions are college football and UFC, and those are the sports he has covered the most. Matthew uses a variety of methods to handicap games, including stats, trends, injuries, and situational factors. His goal is to consistently give out winners and will put in the research to try and achieve this. For Matt Lowrimore media enquiries, please email contact@pickswise.com.
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UFC 303 takes place on Saturday at the T-Mobile Arena in Las Vegas, Nevada. This card features a light heavyweight title fight between Alex Pereira and Jiri Prochazka as the Main Event. Here are our UFC 303 best bets, which will include 3 fights on the Main Card. Be sure to also check out the rest of our UFC predictions for all of the UFC 303 Main Card fights.

UFC 303 Main Card Best Bets

Brian Ortega ML over Diego Lopes (+120)

The Co-Main Event at UFC 303 will see Brian Ortega take on Diego Lopes. This will be a fight in the UFC Featherweight division.

Ortega comes into this fight with an MMA record of 16-3 and he is 8-3 in the UFC. He is averaging 4.07 strikes per minute and has a striking accuracy of 38%. Ortega is absorbing 6.54 strikes per minute and has a striking defense of 49%. His grappling is also solid, averaging 1.17 takedowns per every 15 minutes and 1.2 submission attempts during the same time period. Ortega has a takedown accuracy of 27% and a takedown defense of 57%.

Lopes is billed as the small favorite in this fight, but Ortega has overall been the more impressive fighter. He has proven to be better at striking and as a grappler, therefore backing Ortega to pull off the small upset will be our UFC 303 best bet.

You can also read our UFC 303 parlay at +472 odds!

Anthony Smith ML over Roman Dolidze (+124)

The third fight on the Main Card at UFC 303 will see Anthony Smith take on Roman Dolidze. This will be a fight in the UFC Light Heavyweight division.

Smith comes into this fight with an MMA record of 38-19 and he is 15-11 in the UFC. Smith is averaging 3.23 strikes per minute and has a striking accuracy of 48%. He is also absorbing 4.47 strikes and has a striking defense of 46%. His grappling has been decent at best, averaging 0.49 takedowns per every 15 minutes. He has a takedown accuracy of 26% and has a takedown defense of 49%.

Dolidze is the moderate-sized favorite in this fight, but has shown some inconsistency recently, having lost his last 2 UFC fights in a row. Smith, on the other hand, has the better striking volume and is 2-1 in his last 3 UFC fights. For that reason, backing Smith to pull off the upset will be our next UFC 303 best bet.

Macy Chiasson ML over Mayra Bueno Silva (-110)

The second fight on the Main Card at UFC 303 will see Mayra Bueno Silva take on Macy Chiasson. This will be a fight in the UFC Women’s Bantamweight division.

Chiasson comes into this fight with an MMA record of 10-3 and she is 7-3 in the UFC. Chiasson is averaging 3.53 significant strikes per minute and has a striking accuracy of 44%. She is absorbing 2.53 strikes and has a striking defense of 46%. Her grappling is solid as well, averaging 2.38 takedowns per every 15 minutes. Chiasson has a takedown accuracy of 37% and her takedown defense is 62%.

This fight is very evenly matched, but Chiasson looks to be the right side to play. Where she lacks in striking volume compared to Silva, she more than makes up for in grappling ability. Based on this, backing Chiasson to win will be our final UFC 303 best bet.

Check out the rest of our UFC picks for every main-card fight at UFC 303!

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