Ricky Dimon
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Week 4 of the 2024 NFL regular season is on the immediate horizon, and it’s another one with 2 Monday Night Football games. Before that we have Thursday Night Football showdown in the NFC East (Cowboys vs Giants) plus a whole bunch of division-rivalry matchups such as Saints vs Falcons, Vikings vs Packers and Chiefs vs Chargers.
Make sure you check out our NFL predictions as we add our picks on the side and total for every game throughout the week – and throughout the entire season. Also make sure to check out our NFL best bets page for our top picks. For now, let’s break down the NFL Week 4 opening lines and give our best early bet to make.
NFL Week 4 opening lines and odds
Odds available at DraftKings Sportsbook at time of publishing
Dallas Cowboys -6 (-110) vs New York Giants +6 (-110) – Thursday Night Football
New Orleans Saints OFF vs Atlanta Falcons OFF
Los Angeles Rams +1 (-110) vs Chicago Bears -1 (-110)
Minnesota Vikings +2 (-105) vs Green Bay Packers -2 (-115)
Pittsburgh Steelers -1 (-105) vs Indianapolis Colts +1 (-115)
Jacksonville Jaguars +4.5 (-110) vs Houston Texans -4.5 (-110)
Philadelphia Eagles -2.5 (-110) vs Tampa Bay Buccaneers +2.5 (-110)
Cincinnati Bengals -6.5 (-108) vs Carolina Panthers +6.5 (-110)
Jacksonville Jaguars +4.5 (-110) vs Houston Texans -4.5 (-110)
Washington Commanders +4.5 (-110) vs Arizona Cardinals -4.5 (-110)
New England Patriots +10 (-110) vs San Francisco 49ers -10 (-115)
Cleveland Browns -1 (-110) vs Las Vegas Raiders +1 (-110)
Kansas City Chiefs OFF vs Los Angeles Chargers OFF
Buffalo Bills +2.5 (-110) vs Baltimore Ravens -2.5 (-110) — Sunday Night Football
Tennessee Titans -1 (-105) vs Miami Dolphins +1 (-115) — Monday Night Football
Seattle Seahawks +4.5 (-112) vs Detroit Lions -4.5 (-108) — Monday Night Football
Best bet for NFL Week 4: Baltimore Ravens -2.5 over Buffalo Bills (-110)
The Ravens started 0-2 with a road test against the Cowboys in Week 3. In other words, 0-3 was staring Baltimore in the face. Head coach John Harbaugh’s squad needed a win in the worst way and that is exactly what it got, prevailing in Dallas 28-25.
Now the Ravens return home for a date with the Bills, who will be playing on a short week following their Monday Night Football exploits against the Jaguars. Only 5 days of rest before going on the road to meet of the best teams in the league is not a friendly schedule for Buffalo. Although the Bills are talented, they no longer have Stefon Diggs in their receiver corps and their defense is already quite banged up in the secondary.
With momentum for their first win of 2024 and playing at home against an opponent on short rest, the Ravens have great value giving less than a field goal.
We’ll have NFL Week 4 picks for every game!
