Cleveland Cavaliers vs San Antonio Spurs Prediction, Odds and Picks for Friday, 04/04/25

The San Antonio Spurs are coming into this game after a surprise win against the Denver Nuggets, although their opponents in that game were shorthanded. They will not have the same luxury tonight, when they welcome a Cleveland Cavaliers club that look to have all of their starters available for this one. The visitors still have not clinched the Eastern Conference, so look for them to come in motivated to get a step closer to that so that they can finally start looking ahead to the playoffs. These sides met at the end of March and the lack of size the Spurs had inside was an issue, as they allowed Jarrett Allen a game high 29-points. Look for the Cavs to be able to exploit this once more.

The Spurs have been able to squeeze out wins, but their form suggests they might not be able to sustain this. Over the last 10 games they are 23rd in the league in net offensive and defensive rating. Even if they force misses tonight, over the same stretch of games they are just 22nd in opponent second-chance points per game. The Cavaliers have scored at least 120 points in each of their last 6 games and should be able to use this to smash beyond that mark. With the Spurs in the bottom 10 of the league over the last 10 games in true shooting percentage, it should be hard for them to keep this one competitive.

Cavaliers vs Spurs prediction: Cleveland -13 (-110) available at time of publishing. Playable to -14.

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