Cleveland Cavaliers vs Boston Celtics Prediction, Odds and Picks for Tuesday, 11/19/24

2 of the top teams in the Eastern Conference take center stage on Tuesday night when the undefeated Cleveland Cavaliers travel to TD Garden to take on the defending champion Boston Celtics. Despite the Cavs entering this game a perfect 15-0, oddsmakers are giving them a 5.5-point cushion to work with, favoring the Celtics on their home floor. Boston enters Tuesday’s contest after a 126-123 overtime win over the Toronto Raptors on Saturday and should be well-rested, while the Cavs have some injury concerns with numerous rotation players either listed as out or questionable. Emoni Bates, Dean Wade and Max Strus will all be sidelined, while Caris LeVert, Sam Merrill and Isaac Okoro are currently listed as questionable.

While it’s difficult to bet against an undefeated Cleveland team that’s gone 11-4 against the spread, the amount of injuries they are dealing with might be too much to overcome when facing a tough Boston lineup. The Celtics have gone just 2-4 ATS at TD Garden this season, but they match up quite well with Cleveland. The Celtics pose a significant threat on the perimeter and lead the NBA with an average of 51.1 attempts per game from three-point range while connecting on 37.0% of those attempts. With a thin lineup suiting up for the Cavs, it’s going to be difficult for their interior players to consistently defend the perimeter with sustained success. I’m backing the Celtics to hand Cleveland their first loss of the season while covering the spread in the process.

Cavaliers vs Celtics prediction: Celtics -5.5 (-110) available at time of publishing. Playable at that number.

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