South Carolina Gamecocks vs Missouri Tigers Prediction, Odds and Picks for Tuesday, 02/25/25

Missouri has to be happy to be back home after suffering a crushing loss to Arkansas on Saturday night. The Tigers are 17-1 at home this season, and they’ll be looking to maintain that edge as they prepare to face a pesky South Carolina. South Carolina sits at the bottom in the SEC with a 1-13 conference record, while Missouri is fourth at 9-5. These 2 teams haven’t faced each other yet this season and I think Missouri has a significant edge in tonight’s matchup.

Missouri has to take better control of the ball in this matchup if it wants to win — no questions about it. The Tigers turned the ball over 18 times in their last game against Arkansas, which allowed Arkansas to score an easy 30 points. Not to mention Missouri was foul happy, committing 26 fouls and allowing the Razorbacks to get to the line 37 times. The Gamecocks lost 13 in a row before they snapped that losing streak against Texas on Saturday, but I expect that to be short lived. South Carolina is 1-8 on the road this season, with its last road victory coming against Boston College on December 3. Missouri has an exceptional offense, averaging 83.7 points per game, and I expect that it will be able to clean up its act and limit the number of turnovers and fouls in this contest against a much weaker opponent. SEC matchups are almost always played tough, but South Carolina has struggled this season and is only averaging 70.1 points per game — which gives Missouri a significant edge on offense. If the Tigers can limit their turnovers and not send South Carolina to the free-throw line all the time, they should have no problem covering the spread in this matchup. The Tigers have played exceptionally well at home this season and I expect them to control the pace of this game, this being able to pull away in the second half. 

South Carolina vs Missouri prediction: Missouri -13.5 (-110) available at time of publishing. Playable at that number.

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