Kansas Jayhawks vs Iowa State Cyclones Prediction, Odds and Picks for Today, 01/15/25

One of the biggest showdowns in the Big 12 takes place in the Hilton Coliseum on Wednesday night, and we have your Kansas Jayhawks vs Iowa State Cyclones prediction here. We have a pair of top-10 teams facing off in a classic rivalry spot, and this is must-watch basketball. Iowa State has won 11 straight games, including Saturday’s dramatic overtime win on the road in Lubbock. Kansas is 3-1 in conference play, including a 54-40 slugfest at Cincinnati over the weekend. The Cyclones are favored in this one at home, and while I would like to see a smaller number, I think we can expect Iowa State to keep rolling. I’ll take the Cyclones -6.

I have a suspicion that public money will flow to the Kansas side of the spread before tip-off, so I am waiting and hoping for a couple more points to work with. Kansas is the name brand, and while they are still a dangerous and talented team, they have simply been too inconsistent for me. Said positively, the Jayhawks adapt and win despite their circumstances; said negatively, the Jayhawks too often let the opponent dictate the game. They can’t do that against a team as good as Iowa State. My other concern in this spot is that Iowa State can shoot the heck out of the ball, while Kansas attempts very few outside shots, one of the lowest 3-point rates in the land. If Iowa State gets hot and Kansas refuses to shoot 3s, that is your recipe for the Cyclones winning by a larger margin. Look, I think this Iowa State team is way better than most in the nation yet recognize, and home court in the Big 12 is a massive advantage. I think Iowa State wins this game and covers, but remember to be patient and shop around for the best number.

Iowa State vs Kansas Prediction: Iowa State -6 (-110) available at the time of publishing. Playable at that number.

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