Liberty Flames vs Oregon Ducks Prediction, Odds and Picks for Friday, 03/21/25

The Liberty Flames and the Oregon Ducks will meet in Seattle on Friday for round 1 of the NCAA Tournament. The Big Dance will be in full swing by the time these 2 teams face off, but it should be one of the best games of the day. Liberty has been among the best mid-major teams in the country, winning the Conference USA regular season and tournament championship. Oregon had a great start to the year but finished just eighth in the Big Ten. I like Liberty to keep this game close and cover the 7-point spread.

Liberty +7 is my best bet because it is an elite shooting team and thee defense should be able to limit Oregon’s 3-point shots. According to KenPom, Liberty’s offense is ranked #2 in effective field-goal percentage and #5 in 3-point percentage and #13 in 2-point percentage. The Flames’ offense will likely be good enough to have success Oregon’s defense. Liberty’s defense is ranked #3 in 3-point percentage and #10 in effective field-goal percentage, so Oregon’s points will not come easy. The Flames are a good enough team to keep this game close and potentially pull off a classic 12-over-5 upset. I’m taking Liberty to cover.

Liberty vs Oregon prediction: Liberty +7 (-110) available at time of publishing. Playable to +6.

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