NFL Best Bets

Get our experts’ best NFL bets every week of the 2024/25 season. Our experts analyze their NFL picks and predictions across a whole host of markets to find you their best NFL Bets every week, right here.

Pickswise’s NFL Best Bets went 66-43 for +45 Units of profit throughout the 2023/24 NFL Season.

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Washington Commanders
Sun Jan 26
Philadelphia Eagles
Point Spread PickBest Bet
WAS Commanders +6.5(-115)WAS Commanders @ PHI Eagles

The Commanders and Eagles will meet for a 3rd time this season and while the entire football world is engrossed over the enigma that is Jayden Daniels, apparently the market doesn’t agree. The Eagles have risen from -4.5 opening chalk to now as high as -6.5 favorites at many books, an understandable designation but one that will undoubtedly allure many public bettors to put some hard-earned cash on Washington’s new prodigy — and we don’t blame them!

Daniels is mystifying, showing poise and exceptional in-game decision-making as if he’s been in the NFL for a decade. He presents a very Patrick Mahomes-like demeanor, with an equally Mahomes-like ability to make plays either with his arm or legs in unconventional ways. As we’ve seen many times before, a franchise can be very flawed and still win championships when they get their coach and quarterback right, and it seems that’s what the Commanders are moving towards. Last weekend, Daniels was nearly perfect, throwing 22-31 for 299 yards, 2 touchdowns, and another 51 yards on the ground. No one would have predicted this prodigious climb in year 1 of Daniels’ career, but the Commanders are responding and playing exceptionally well across their roster.

Last week, in Detroit, the Commanders forced Jared Goff into 3 uncharacteristic interceptions. They immediately put pressure on the Lions’ esteemed thrower, sacking him twice and knocking him down another 7 times. Goff was under constant duress, and while the Lions still gained 521 yards and 31 points, we still consider it a major win for their defense. The Lions are always an offensive juggernaut at home, but most of their production was gained because they were playing from behind. Fascinatingly, after Washington went up 17-14 halfway through the 2nd quarter, Detroit never gained another lead, so Goff and a desperate offense were playing catchup for 63% of the game.

We have less to say about the Eagles because we’re not as impressed. Winning at home against a program you’ve always matched up well against is, at this point, an expectation for the Eagles, but the truth is they barely got past the Rams. Saquon Barkley (205 rushing yards) and a tenacious defense (5 sacks, forced 2 turnovers) were the 2 biggest reasons why they succeeded, factors that we’re certainly considering as this Sunday approaches. Still, for the 2nd straight week, Jalen Hurts and the pass-offense was rather anemic, accruing just 65 total passing yards. Hurts was also sacked 7 times and they just couldn’t put the game away like we’ve seen so many times in the past.

Washington coach Dan Quinn and of course rookie sensation Daniels are less experienced in these big-game situations in the NFL. We could care less. Daniels and his colleagues have shown that they can handle the pressure and that only amplifies when you consider the familiarity of a divisional opponent. Over their past 4 meetings, the Commanders are 1-3, but they’ve only lost by 3, 7 and 8-point margins, and they were all before they had Daniels in his current form. We’re going with the dog.

Commanders vs Eagles prediction: Commanders +6.5 (-115) available at time of publishing. Playable to 5.5.

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Chris R. Farley
Buffalo Bills
Sun Jan 26
Kansas City Chiefs
Point Spread PickBest Bet
KC Chiefs -1.5(-115)BUF Bills @ KC Chiefs

In what promises to be another legendary matchup, Patrick Mahomes and Josh Allen will meet for the 4th time in the last 5 years of the AFC playoffs. In every one of the last 3 wars, the Chiefs have come out the victor, although it’s worth noting that their last 2 wins were extremely close (one required overtime, the other decided by just a field goal). With all that in mind, it’s not a mystery why the spread sits at a humble -1.5 in favor of the home team, a designation that suggests oddsmakers think that these 2 outfits are relatively even.

Of course, it’s very hard to measure the Kansas City Chiefs and their winning ways. Short-minded prognosticators will point towards fortunate penalties and lucky bounces as the reasons why KC just keeps succeeding, but we know better. The combination of Andy Reid and Patrick Mahomes is second to none, a synergistic partnership that reflects the peak of championship form, especially in the game’s most pressurized moments. Yes, we know, it’s not always in the stats, but Mahomes tends to find a way when his team needs it, and so does his favorite target, Travis Kelce. Taylor Swift’s boyfriend had a mediocre season, especially compared to his previous standards, but one game into the postseason and he grabs 7 catches (on 8 targets) for 117 yards and a touchdown. If it wasn’t Kelce, it would have been someone else, and it’s not like they don’t have the talent. Isiah Pacheco, Hollywood Brown, rookie Xavier Worthy and the second-chance kid, Kareem Hunt, have all been game changers before. The KC defense was also ultra-impressive, sacking a feisty CJ Stroud 8 times and limiting Houston in the most integral moments. For example, the Texans were 1-3 in the red zone and scored just 2 points in the 4th quarter. At Arrowhead, we can’t remember the last time an offense exploded against the home team; it just doesn’t happen very often.

But if any team is ready to get by the Chiefs, it’s the Bills, and they already did it once this season. Back in Week 11, Buffalo executed a superior game plan against their rival, preventing Mahomes and the Chiefs’ offense from ever launching into a big lead. Buffalo forced an interception on Kansas City’s very first drive, capitalizing on it for a quick touchdown lead, and later they forced another interception on Mahomes’ last drive, effectively ending the contest. Josh Allen was magnificent, finishing the match with 2 straight touchdown drives in the 4th quarter. Allen was responsible for 145 of those 153 combined yards, either by running or passing.

One was left wondering what would have happened if Mahomes never threw those 2 interceptions, and now he’ll have the chance to seek revenge at home. Our favorite bet on this game is teasing up Buffalo to +7.5 or +8, but Kansas City is at home and now they’re seeking “revenge,” however superficial it may be, from their loss earlier this season. They’re also seeking to be the first team in NFL history to win 3 straight Super Bowls; it doesn’t get more motivating than that. Mahomes and Reid don’t typically trip twice against the same program, and they own the better defense. As much as we’d like to see Buffalo in the big dance, we can’t bet with our hearts.

Bills vs Chiefs prediction: Chiefs -1.5 (-115) available at time of publishing. Playable to 2.5.

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Chris R. Farley
NFL Best Bets
52.3%
Win %
56Wins
51Losses
1Pushes
Percentage only includes Wins and Losses

NFL Video

At Pickswise our experts put in countless hours of research and analysis every week to bring you free NFL best bets. Although the NFL regular season is just 18 weeks long, there are still 272 regular-season NFL games to decipher, as well as the NFL playoffs, and we bring you free NFL best bets across the whole season and post-season.

What Is An NFL Best Bet at Pickswise?

Our expert NFL cappers, post their best bets on this week’s NFL games across a whole host of betting markets. Each of our selections on Pickswise is given a confidence rating ranging from 1 to 3 stars, with 3 stars being the most confident, and 1 the least. Our NFL Best Bets page details just that, our expert NFL Best Bets on this week’s games.

How Did Pickswise’s NFL Best Bets Perform Last Season?

The expert NFL handicappers at Pickswise saw great success throughout the 2023/24 NFL season and their best bets were no different. We post multiple best bets each week of the season, all accompanied by analysis, data and trends that are all fact-checked by our editors. Check out our 2023/24 NFL Best Bets records below;

2023-24 NFL Best Bets Record
WinLossProfit/Loss
6643+45 Units

NFL Best Bets Today

The NFL action comes thick and fast during the season and we cover all of it. The NFL Best Bets page should be your first port of call here at Pickswise alongside the NFL Picks page where you can find the entire catalog of our weekly game previews which combine for a comprehensive view of all of today’s NFL games and best bets. Check back every week for those Monday Night, Thursday Night and Sunday slates’ best NFL picks, all for free. 

Best Bets For NFL This Week

The NFL is very much a look-ahead sport, particularly within sports betting. Almost as soon as the previous week’s games are done, oddsmakers and bettors alike are already trying to find the best bets for NFL this week. Here at Pickswise, we’re no different. You can often find great value early in the week and our experts will take an early look ahead every week, and aim to get our best bets for NFL this week posted on-site as soon as possible, to try to lock in those best lines and odds. Be sure to keep an eye on the NFL best bets page every day on game week as our experts continue to highlight those biggest edges and best NFL bets.

Where Should I Bet On Your NFL Best Bets Today

Another important strategy for maximizing your NFL betting success is to make sure you have access to the best odds and lines available across all of the best online sportsbooks.

Alongside our NFL best bets, we also highlight the best odds and lines that the sportsbooks are currently offering. This ensures you’re maximizing your chances of turning a profit over time as every half point or fractional odds difference adds up over time.

Unsure where is best to place your online sports wagers? Or looking to make the most of new player bonuses and promo codes? Be sure to check out our
Online Sportsbook Promotions for expert analysis of the best sportsbook welcome offers available in your state. 


+45 Units from 2023/24 NFL Best Bets

When Pickswise tells you that we have an NFL Best Bet, we mean it. In the 2023 season, our team of expert NFL handicappers finished +45 units in profit on our best bets and we are hungry to provide even more winners this season. We don’t just throw around 3 star plays, all of our cappers and editors meticulously break down each pick and predictions before we put our NFL best bet stamp on it. We often have best bets each week of the season, but tail our expert NFL cappers with confidence this week. 

Andrew Wilsher, Pickswise Managing Editor

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NFL Best Bets FAQs

There are endless ways in which you can bet on the NFL and the Best Bet is a winning one. The Pickswise Best Bets page is a collation of our expert handicappers’ most confident selections on this week’s NFL games. While we can’t guarantee every bet will win, we have a long-trusted and proven record, our NFL Best Bets saw a return of +45 units across the 2023/24 season.

The most important numbers to consider when betting on the NFL are 3 and 7. A lot of games in the NFL are decided by one score so when you’re looking at spread lines you must keep Field Goals and Touchdowns at the forefront of your mind, as there is a big difference between -3.5 and -2.5 and -6.5 and -7.5.

At Pickswise we use a star system to show our cappers’ confidence in that particular pick. All of our Best NFL Bets get our top confidence rating of 3 stars.

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