Manchester United vs Southampton Prediction, Odds and Picks for Tomorrow, 01/16/25

Manchester United may have failed to win any of their last 6 matches across all competitions inside 90 minutes, but they have shown signs in their last 2 performances that they are now finding their feet under head coach Ruben Amorim. The Red Devils followed up an impressive 2-2 tie at leaders Liverpool in their last league game with Sunday’s penalty shootout triumph at Arsenal in the FA Cup, a match that finished 1-1 after extra time despite United playing for an hour with 10 men. Those results and performances should have boosted United’s confidence ahead of this home clash with bottom-of-the-table Southampton, while Thursday’s hosts also have an impressive recent record when facing the Saints, as they are unbeaten in the last 16 meetings between the 2 teams. That sequence includes a 9-0 success for United at Old Trafford in 2021, although their 2 home meetings with Southampton since then have both finished as ties.

Like United, Southampton also enjoyed success in the FA Cup at the weekend, as they comfortably defeated Championship club Swansea 3-0 at St. Mary’s Stadium to hand manager Ivan Juric his first win since taking charge last month. That result also snapped an 11-game winless run across all competitions for the Saints, but they remain with just 1 league success to their name all season and are cut adrift at the bottom of the standings. The south coast club are the only team yet to win on the road in the EPL this term and their last victory at Old Trafford came almost 9 years ago. However, they should be motivated by the 3 goals they scored against Swansea and Southampton are certainly capable of getting on the scoresheet, so backing a United victory with both teams finding the net makes sense.