Arsenal vs PSV Prediction, Odds and Picks for Today, 03/12/25

Arsenal take on PSV in the second leg of their Champions League Last 16 tie on Wednesday with a place in the quarterfinals virtually guaranteed. The Gunners won 7-1 in the first leg in Eindhoven, recording the largest-ever road win in the knockout stages of the Champions League, and it would take an unprecedented turnaround for their European campaign to end this week. However, that does make this game a little harder to navigate. PSV will be keen to restore some pride even if they know they have almost no chance of progress, while Arsenal boss Mikel Arteta may even use this chance to rest a few players – although he will still name a strong side. As such, Arsenal are worth avoiding as a heavy favorite against a team that has  picked up results against PSG, Liverpool and Juventus this season, so the best option looks to be for there to be goals at both ends.

PSV did manage to get on the scoresheet in the first leg and they can at least land a glancing blow on Arsenal in North London. The Dutch club has seen goals at both ends in each of their last 8 games and have only failed to score in 1 Champions League game, grabbing goals against the likes of Sporting Lisbon, Juventus (in all 3 meetings), PSG, Liverpool and Shakhtar Donetsk along the way. Arsenal have found shutouts hard to come by of late, particularly at home where they have conceded in 6 of their last 7 games, but they have only failed to score in 3 home games all season and should be able to play their part in finding the net as well.