San Francisco 49ers vs Arizona Cardinals Prediction, Odds and Picks for Tomorrow, 01/05/25
LWLLL | Last 5 | LLWLL |
| 6-10 | Record | 7-9 |
| 5-11-0 | ATS Record | 10-6-0 |
| 8-8 | O/U Record | 7-9 |
Vote on who will cover the spread!
49ers vs Cardinals Pickswise Expert Predictions
The 49ers showed some fighting spirit in their narrow 40-34 loss to the Lions on Monday Night Football last week, but it came at a price as quarterback Brock Purdy exited towards the end of the game with an injured elbow. With nothing to play for, it is unlikely that Purdy will suit up for this game, but even with that in mind, San Francisco should have a decent shot at covering this spread. Last season’s superstar backup Josh Dobbs came in for Purdy last week and put in a decent showing in his sole drive, completing 3 of 4 passes for 35 yards before running the ball in for a touchdown. Rookie receiver Ricky Pearsall had a great game with 141 yards and a touchdown, while George Kittle also reached triple digits in yardage. This 49ers team should continue to play hard in the final game of the season and the offense can do some damage against a defense that ranks in the bottom 10 in passing yards per attempt allowed and 5th-worst in opponent completion percentage.
Meanwhile, the Cardinals were thwarted by the Rams last Saturday to secure the NFC West title for LA. Arizona played hard on offense with Kyler Murray connecting with Trey McBride for 12 receptions, 123 yards and a touchdown. However, the Cards have still lost 5 of their last 6 games, and their only victories since the start of November have come over the lowly Bears, Jets and Patriots. Even with Purdy out, it’s a lot to ask for this Arizona team to cover this spread, especially with running back James Conner ruled out and against a 49ers defense that allows the 4th-fewest passing yards per attempt. The Niners look a solid underdog in this one.
49ers vs Cardinals prediction: 49ers +4.5 (-110) available at time of publishing. Playable at that number.
You can bet on our 49ers vs Cardinals pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and get up to $1,500 in first-bet protection!
Andrew Wilsher
Show Bio
The Cardinals have lost 5 of their last 6 games.
The average total game score (50.5) in the 49ers' last 10 road games is Over this game's current total (43.0).
The 49ers are 1-6 against the spread on the road this season.
Coins
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
Sign up for an account with Sportzino
You’ll get a 1,570,000 Gold Coins + 45 free Sweeps Coins upon signup
Start making bets with the at the Sportzino Social Sportsbook & Casino
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
Coins
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
Sign up for an account with Sportzino
You’ll get a 1,570,000 Gold Coins + 45 free Sweeps Coins upon signup
Start making bets with the at the Sportzino Social Sportsbook & Casino
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
COINS
Sign up to get 15,000 Gold Coins + 2.5 free Sweepstakes Coins
Sign up for a new Hello Millions casino account
Sign up to get 15,000 Gold Coins + 2.5 free Sweepstakes Coins
First-purchase bonus: 230,000 GC + 115 SC for $69.97 over first three purchases
Available to players aged 18 and up only. Gambling problem? Call 1-800-GAMBLER.
COINS
No Deposit Bonus: 5,000 Gold Coins + 2.3 Sweeps Coins!
Sign up for a new Pulsz casino account
Get 5,000 free GCs and 2.3 SCs simply by registering using code PW01
Get 362,000 GC and 30 Pulsz with a purchase of $19.99
Available to players aged 18 and up only. Gambling problem? Call 1-800-GAMBLER.
COINS
Sign up to get 7,500 Gold Coins + 2.5 free Sweepstakes Coins!
Sign up for a new McLuck casino account
Get 7,500 Gold Coins + 2.5 free Sweepstakes Coins when you sign up
150% extra coins: GC 50,000 + SC 25 FREE for $9.99
Available to players aged 18 and up only. Gambling problem? Call 1-800-GAMBLER.
COINS
Sign up to get 7,500 Gold Coins + 2.5 free Sweepstakes Coins
Sign up for a new McLuck casino account
Get 7,500 Gold Coins + 2.5 free Sweepstakes Coins when you sign up
150% extra coins: GC 50,000 + SC 25 FREE for $9.99
Available to players aged 18 and up only. Gambling problem? Call 1-800-GAMBLER.
COINS
No Deposit Bonus: 5,000 Gold Coins + 2.3 Sweeps Coins
Sign up for a new Pulsz casino account
Get 5,000 free GCs and 2.3 SCs simply by registering using code PW01
Get 362,000 GC and 30 Pulsz with a purchase of $19.99
Available to players aged 18 and up only. Gambling problem? Call 1-800-GAMBLER.
$50
Sign up and get a $50 Deposit Bonus + Player Pick for Free!
Sign up with SuperDraft using code PICKSWISE
Make your deposit up to $50 and receive the top SuperDraft welcome bonus
Start playing pick\'em and win up to 5000x payout
Must be 18+. Terms and conditions apply to all offers. Please see SuperDraft for details. Gambling Problem? Call 1-800-GAMBLER+
$50
Sign up and get a $50 Deposit Bonus + Player Pick for Free
Sign up with SuperDraft using code PICKSWISE
Make your deposit up to $50 and receive the top SuperDraft welcome bonus
Start playing pick\\\'em and win up to 5000x payout
Must be 18+. Terms and conditions apply to all offers. Please see SuperDraft for details. Gambling Problem? Call 1-800-GAMBLER+
$50
Sign up and get a $50 Deposit Bonus + Player Pick for Free
Sign up with SuperDraft using code PICKSWISE
Make your deposit up to $50 and receive the top SuperDraft welcome bonus
Start playing pick'em and win up to 5000x payout
Must be 18+. Terms and conditions apply to all offers. Please see SuperDraft for details. Gambling Problem? Call 1-800-GAMBLER+
$1,000
Bet and Get up to $1,000 in No Sweat Bets!
Sign up for a new Fanatics Sportsbook account.
Your first bet each of the 10 days is matched by 100%, for a maximum of $100 in No Sweat Bets daily.
Get up to a total of $1,000 in No Sweat Bets.
Must be 21+ to participate. | T&Cs apply. | Play Responsibly. | Gambling problem? Call 1-800-522-4700; AZ 1-800-NEXT-STEP; CT (888) 789-7777; MA (800)-327-5050; NY 877-8-HOPENY or text HOPENY (467369); VA 1-888-532-3500; CO, IA, KS, KY, MD, NJ, OH, PA, TN, VT, WV 1-800-GAMBLER; MD Please play responsibly, for help visit mdgamblinghelp.org or call 1-800-GAMBLER
$1,000
Bet and Get up to $1,000 in No Sweat Bets!
Sign up for a new Fanatics Sportsbook account.
Your first bet each of the 10 days is matched by 100%, for a maximum of $100 in No Sweat Bets daily.
Get up to a total of $1,000 in No Sweat Bets.
Must be 21+ to participate. | T&Cs apply. | Play Responsibly. | Gambling problem? Call 1-800-522-4700; AZ 1-800-NEXT-STEP; CT (888) 789-7777; MA (800)-327-5050; NY 877-8-HOPENY or text HOPENY (467369); VA 1-888-532-3500; CO, IA, KS, KY, MD, NJ, OH, PA, TN, VT, WV 1-800-GAMBLER; MD Please play responsibly, for help visit mdgamblinghelp.org or call 1-800-GAMBLER
$1,000
Bet and Get up to $1,000 in No Sweat Bets!
Sign up for a new Fanatics Sportsbook account.
Your first bet each of the 10 days is matched by 100%, for a maximum of $100 in No Sweat Bets daily.
Get up to a total of $1,000 in No Sweat Bets.
Must be 21+ to participate. | T&Cs apply. | Play Responsibly. | Gambling problem? Call 1-800-522-4700; AZ 1-800-NEXT-STEP; CT (888) 789-7777; MA (800)-327-5050; NY 877-8-HOPENY or text HOPENY (467369); VA 1-888-532-3500; CO, IA, KS, KY, MD, NJ, OH, PA, TN, VT, WV 1-800-GAMBLER; MD Please play responsibly, for help visit mdgamblinghelp.org or call 1-800-GAMBLER
JOIN
Use Code PICKSWISE to get 35% off your First Month and Beat the Sportsbooks!
OddsJam offers the most comprehensive odds comparison tools and betting tools
Unlock your betting potential with industry-leading OddsJam
OddsJam is the #1 betting tool for winners, offering arbitrage and positive EV tools to help you beat the sportsbooks
This site is 100% for entertainment purposes only and does not involve real money betting. If you or someone you know has a gambling problem and wants help, call 1-800 GAMBLER.
Ticket
New Users Get A Free Lottery Ticket on Their First Deposit!
Sign up for a lottery account with Jackpot.com
New users get a free ticket on their first deposit
Use promo code Pickswise
If you or someone you know needs support, professional help is available 24/7. If you or a loved one has questions or needs to talk to a professional about gambling, call 1-800-GAMBLER or visit 1800gambler.net for more information.
Ticket
New Users Get A Free Lottery Ticket on Their First Deposit
Sign up for a lottery account with Jackpot.com
New users get a free ticket on their first deposit
Use promo code Pickswise
If you or someone you know needs support, professional help is available 24/7. If you or a loved one has questions or needs to talk to a professional about gambling, call 1-800-GAMBLER or visit 1800gambler.net for more information.
Coins
Get 1.5 million WOW Coins + 35 FREE Sweepstake Coins
Sign up for WOWVegas social casino
Receive 1.5 million WOW Coins up signup
Plus 35 FREE Sweepstake Coins
*Sweeps Play available in the United States, excluding Michigan, Washington, Nevada and Idaho. Persons under the age of 18 are not permitted to create accounts and/or participate in the games. **Only one Sweepstakes eligible account per player.
Coins
Get 1.5 million WOW Coins + 35 FREE Sweepstake Coins
Sign up for WOWVegas social casino
Receive 1.5 million WOW Coins up signup
Plus 35 FREE Sweepstake Coins
*Sweeps Play available in the United States, excluding Michigan, Washington, Nevada and Idaho. Persons under the age of 18 are not permitted to create accounts and/or participate in the games. **Only one Sweepstakes eligible account per player.
Coins
Get 1.5 million WOW Coins + 35 FREE Sweepstake Coins
Sign up for WOW Vegas social casino
Receive 1.5 million WOW Coins up signup
Plus 35 FREE Sweepstake Coins
*Sweeps Play available in the United States, excluding Michigan, Washington, Nevada and Idaho. Persons under the age of 18 are not permitted to create accounts and/or participate in the games. **Only one Sweepstakes eligible account per player.
$250
Bet $5, Get $250 in Bonus Bets if your bet wins
Sign up for a new FanDuel Sportsbook account
Bet $5 on any sport
Get $250 in bonus bets if your bet wins
Gambling Problem? Call 1-800-GAMBLER. Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ and present in select states. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).
$1500
Get Up To $1500 in Bonus Bets Paid Back if your First Bet Doesn't Win
Register for a new BetMGM account & deposit
Place your first bet up to $1,500
Get Up To $1500 in Bonus Bets Paid Back if your First Bet Doesn't Win
21+ to wager. Please Gamble Responsibly. Gambling problem? Call 1-800-GAMBLER. Visit BetMGM.com for Terms & Conditions. US promotional offers not available in DC, Nevada, New York or Ontario. Bonus Bets Expire in 7 Days.
$150
Bet $5, Get $150 in Bonus Bets Instantly
Sign up for a new account with DraftKings Sportsbook and make your first deposit
Bet $5 on any sports market and get $150 in bonus bets instantly
Must be 21+. Gambling Problem? If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537). See terms at sportsbook.draftkings.com.
$1,000
Bet $5 and Get $150 in Bonus Bets!
Register for a new bet365 account
Place $5+ and get $150 in bonus bets - no matter if your bet wins or loses
OR $2,000 back in bonus bets if your first bet loses
Gambling problem? Call 1-800-GAMBLER. 21+. Physically present in OH, CO, NJ, VA, IA, KY, LA, AZ, IN. Eligibility restrictions apply. Subject to regulatory licensing requirements. Opt-in req. Valid 1 per customer.
Diamonds
Get 3 Sweeps Coins, 250 Game Coins and 50 Diamonds
*Sweeps Play only available in the United States, excluding Michigan, Washington, Nevada and Idaho. High 5 Casino Classic features are still available in all other legal states! **Only one Sweepstakes eligible account per player.
Diamonds
Get 3 Sweeps Coins, 250 Game Coins and 50 Diamonds
*Sweeps Play only available in the United States, excluding Michigan, Washington, Nevada and Idaho. High 5 Casino Classic features are still available in all other legal states! **Only one Sweepstakes eligible account per player.
Diamonds
Sign up and Get 50 Diamonds, 250 Game Coins and 3 Sweeps Coins!
Sign up for a new High 5 Social Casino account
Receive a no-deposit bonus of 3 Sweep Coins and 250 Game Coins just for signing up
Plus you’ll have 50 diamonds to boost your gameplay
*Sweeps Play only available in the United States, excluding Michigan, Washington, Nevada and Idaho. High 5 Casino Classic features are still available in all other legal states! **Only one Sweepstakes eligible account per player.
$1500
Up To $1500 in Bonus Bets Paid Back if your First Bet Doesn't Win
Register for a new BetMGM account & deposit
Place your first bet up to $1,500
Get Up To $1500 in Bonus Bets Paid Back if your First Bet Doesn't Win
21+ to wager. Please Gamble Responsibly. Gambling problem? Call 1-800-GAMBLER. Visit BetMGM.com for Terms & Conditions. US promotional offers not available in DC, Nevada, New York or Ontario.
$150
Bet $5, Get $150 in Bonus Bets Instantly
$1,000 First Bet on Caesars!!
21+. New users and first wager only. See Caesars.com/promos for full terms. Know When To Stop Before You Start.® Gambling problem? Call 1-800-GAMBLER. MA: CALL 1-800-327-5050 NY: Call 877-8-HOPENY or text HOPENY (467369)
$250
Bet $5, Get $250 in Bonus Bets if your bet wins
Sign up for a new FanDuel Sportsbook account
Bet $5 on any sport
Get $250 in bonus bets if your bet wins
Gambling Problem? Call 1-800-GAMBLER. Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ and present in select states. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).
$1,000
First Time Deposit Offer up to $1,000 in Bonus Cash
Sign up for a new account with Underdog Fantasy
Make your first deposit up to $1,000
Get a 100% deposit match, and new users can get up to $1,000 in bonus cash on their first deposit
Must be 21+ to play. Terms & conditions apply
$1,000
First Time Deposit Offer up to $1,000 in Bonus Cash
Must be 21+ to play. Terms & conditions apply
$250
Bet $5, Get $250 in Bonus Bets if your bet wins
Sign up for a new FanDuel Sportsbook account
Bet $5 on any sport
Get $250 in bonus bets if your bet wins
Gambling Problem? Call 1-800-GAMBLER. Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ and present in select states. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).
$250
Bet $5, Get $250 in Bonus Bets if your bet wins
Sign up for a new FanDuel Sportsbook account
Bet $5 on any sport
Get $250 in bonus bets if your bet wins
Gambling Problem? Call 1-800-GAMBLER. Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ and present in select states. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).
$1,000
$1,000 First Bet on Caesars
21+. New users and first wager only. See Caesars.com/promos for full terms. Know When To Stop Before You Start.® Gambling problem? Call 1-800-GAMBLER. MA: CALL 1-800-327-5050 NY: Call 877-8-HOPENY or text HOPENY (467369)
$150
Bet $5, Get $150 in Bonus Bets Instantly
Sign up for a new account with DraftKings Sportsbook and make your first deposit
Bet $5 on any sports market and get $150 in bonus bets
Gambling Problem? Call 877-8-HOPENY/text HOPENY (467369) (NY), If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (CO/IL/IN/LA/MD/MI/NJ/PA/TN/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (KS), 888-789-7777/visit ccpg.org (CT), 1-800-BETS OFF (IA), or 1-888-532-3500 (VA). 21+ (18+ WY). Physically present in AZ/CO/CT/IL/IN/IA/KS/LA(select parishes)/MD/MI/NJ/NY/PA/TN/VA/WV/WY only. Void in OH/ONT. Eligibility restrictions apply. Valid 1 per new customer. Min. $5 deposit. Min. $5 bet. $200 issued as bonus bets that expire 7 days (168 hours) after being awarded. See terms at sportsbook.draftkings.com.
$1000
$1,000 First Bet on Caesars!
Sign up for a new Caesars Sportsbook account and Place your 1st wager of $10 or more
Place your first wager up to $1,000
If the bet loses, earn a one-time Bonus Bet token equal to the qualifying wager
21+. New users and first wager only. See Caesars.com/promos for full terms. Know When To Stop Before You Start.® Gambling problem? Call 1-800-GAMBLER. MA: CALL 1-800-327-5050 NY: Call 877-8-HOPENY or text HOPENY (467369)
$250
Bet $5, Get $250 in Bonus Bets if your bet wins
Sign up for a new FanDuel Sportsbook account
Bet $5 on any sport
Get $250 in bonus bets if your bet wins
Gambling Problem? Call 1-800-GAMBLER. Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ and present in select states. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).
$150
Bet $5, Get $150 in Bonus Bets Instantly
Sign up for a new account with DraftKings Sportsbook and make your first deposit
Bet $5 on any sports market and get $150 in bonus bets
Gambling Problem? Call 877-8-HOPENY/text HOPENY (467369) (NY), If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (CO/IL/IN/LA/MD/MI/NJ/PA/TN/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (KS), 888-789-7777/visit ccpg.org (CT), 1-800-BETS OFF (IA), or 1-888-532-3500 (VA). 21+ (18+ WY). Physically present in AZ/CO/CT/IL/IN/IA/KS/LA(select parishes)/MD/MI/NJ/NY/PA/TN/VA/WV/WY only. Void in OH/ONT. Eligibility restrictions apply. Valid 1 per new customer. Min. $5 deposit. Min. $5 bet. $200 issued as bonus bets that expire 7 days (168 hours) after being awarded. See terms at sportsbook.draftkings.com.
$1,000
$1,000 First Bet on Caesars
Sign up for a new Caesars Sportsbook account and Place your 1st wager of $10 or more
Place your first wager up to $1,000
If the bet losses, earn a a one-time Bonus Bettoken equal to the qualifying wager
21+. New users and first wager only. See Caesars.com/promos for full terms. Know When To Stop Before You Start.® Gambling problem? Call 1-800-GAMBLER. MA: CALL 1-800-327-5050 NY: Call 877-8-HOPENY or text HOPENY (467369)
$1,000
Bet $5 and Get $150 in Bonus Bets OR $1,000 Back If Your First Bet Loses
Register for a new bet365 account
Place $5+ and get $150 in bonus bets - no matter if your bet wins or loses
OR $1,000 back in bonus bets if your first bet loses
Gambling problem? Call 1-800-GAMBLER. 21+. Physically present in OH, CO, NJ, VA, IA, KY, LA, AZ, IN. Eligibility restrictions apply. Subject to regulatory licensing requirements. Opt-in req. Valid 1 per customer. Deposit required. Paid in Bonus Bets. Bonus Bets wager excluded from returns. New Customers only. T&Cs, time limits and exclusions apply
$1,000
First Time Deposit Offer up to $1,000 in Bonus Cash
Sign up for a new account with Underdog Fantasy
Make your first deposit up to $1,000
Get a 100% deposit match, and new users can get up to $1,000 in bonus cash on their first deposit
Must be 21+ to play. Terms & conditions apply
NFL Video
NFL Analysis
See All NFL News
Cleveland Browns vs Baltimore Ravens Same Game Parlay: Lamar Jackson makes MVP case at +850 odds
The penultimate day of the 2024 NFL regular season features AFC North competition, starting with the Baltimore Ravens hosting the Cleveland Browns. Baltimore controls its own destiny in the division,...
