Arizona Cardinals vs Seattle Seahawks Prediction, Odds and Picks for Sunday, 11/24/24

The Arizona Cardinals have been one of the biggest surprises across the league this season, particularly in recent weeks with convincing victories over the Bears and Jets that have put Arizona into first place in a jam-packed NFC West division. What was most impressive in those victories was the Cardinals defense, as Arizona held Chicago and New York to a combined 15 points over those two wins, which further speaks to the excellent coaching job that Jonathan Gannon has done in his short tenure in Arizona. With that said, I’m not convinced that those wins have aged all that well, especially given how the offenses of the Bears and Jets looked in losses a week ago.

While the Cardinals have generated some hype in recent weeks, the same can’t be said for a Seahawks team that is suddenly very much in the division and wild card picture after rallying to upset the 49ers on the road a week ago. Mike Macdonald’s defense is getting healthier and the results certainly showed in a big way against a strong San Francisco offense coming out of the bye week, and I don’t think that effort was a one-off occurrence. The Seahawks will likely stick to a lot of two-high safety looks and put a roof on the explosive play potential of this Cardinals passing offense, which should force Arizona to be a bit more methodical and lean on its ground game on early downs. On the other side, Geno Smith has often played his best football in big moments this season, and I’d expect that to continue against a Cardinals pass defense that is still one of the weaker units in the league. Let’s take the Seahawks on the money line in what should be a true coin flip game in Seattle.

Cardinals vs Seahawks prediction: Seahawks ML (-110) available at time of publishing. Playable at that number.

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There are obviously paths for both teams to win this game, but I still lean toward the under, regardless of which side wins the game. Seattle’s offensive line continues to be a major issue, with the Seahawks sitting at 25th in pass-block win rate on the season. Smith could be under pressure early on in this one, and offensive coordinator Ryan Grubb has shown that he has no problem with running the ball and trusting the short passing game to be an extension of the running game on early downs. The Seahawks defense is much stronger against the pass than the run, so I wouldn’t be surprised if the Cardinals put the ball in James Conner’s hands and rely on the ground game to put Kyler Murray in advantageous situations on 3rd down. As long as both defenses can do a decent job of limiting explosive plays, we should be heading for a game played in the mid 20s on Sunday.

Under 48 available at time of publishing. Playable at that number.