Andrew Wilsher
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College football is officially back, and we’ve got some interesting Week 0 action here as the Wyoming Cowboys battle the Illinois Fighting Illini. Both teams will be keen to kick things off with a win, and it will be interesting to see how Illinois perform after their rebuilding season in 2021. We have odds, best bets and picks for Wyoming vs Illinois right here, but make sure you also check out our College Football picks page, where we provide bets on the side and total for every game involving a Power 5 conference team.
Wyoming vs Illinois odds
Odds courtesy of DraftKings Sportsbook
Wyoming Cowboys vs Illinois Fighting Illini money line odds
Wyoming Cowboys (+420)
Illinois Fighting Illini (-540)
Wyoming Cowboys vs Illinois Fighting Illini spread odds
Wyoming Cowboys -13.5 (-110)
Illinois Fighting Illini -13.5 (-110)
Wyoming Cowboys vs Illinois Fighting Illini over/under game total odds
Over 44 (-110)
Under 44 (-110)
Wyoming vs Illinois spread prediction: Wyoming +13.5 (-110)
Illinois was going through a rebuild in 2021 and they look to kick things off in 2022 with a win over Wyoming. A 4-0 start is possible for the Illini, but don’t be surprised if Wyoming at least pushes them close. Illinois coach Bret Bielema will likely continue to focus on the run game given his offense averaged 170 rushing yards per game last season.
However, one factor that is alarming for Illini bettors is that they scored over 25 points just three times in 2021. Laying nearly two touchdowns would leave very little room for error for their defense. Wyoming had one of the best defenses in the Mountain West conference last year and has the ability to keep Illinois somewhat in check. And if the Illini focus on their run game, that would mean the clock keeps ticking. It’s tough to see a Cowboys win, but they can at least keep things respectable.
Be sure to check out our Wyoming vs Illinois predictions
Wyoming vs Illinois over/under prediction: Under 44 (-110)
A lot of what was said above also applies to why taking under 44 points to be scored looks to be a smart move. Both defenses were strong last season, with the Illini allowing an average of 21 points per game while the Cowboys allowed 24. Illinois’ focus on the run should keep the clock ticking and therefore fewer plays and possessions as a result, but it’s also worth bearing in mind that both teams will be playing with a rookie quarterback. As a result, both Illinois and Wyoming will likely look to ease their QBs into the game. Take the under.
Don’t forget to read our CFB Week 0 mega parlay!
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