Andrew Wilsher
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Welcome to the Pickswise NFL Week 16 betting guide — our experts have done the research so you have everything you need to beat your book below!
NFL Week 16 picks
Pickswise NFL show
Watch the Pickswise NFL show with Rachael Van Oranje and Jeff Reinebold every Thursday on YouTube, as they break down all the big games in Week 16 and give their Parlay of the Week.
NFL Week 16 betting guides
- Best underdog picks
- Man vs. Machine computer picks
- Pickswise NFL Power Rankings
- Public betting trends
- Daily Fantasy picks
- Fantasy football: start ’em, sit’em
- 6-team money line mega parlay (+6598)
Game previews & computer picks
For the 2020 NFL season, we have introduced NFL computer picks against the spread into our individual game previews. They give you a deeper analysis into the game over the picks write-ups on the main NFL picks page. The Pickswise supercomputer will give probabilities and projections for the main NFL betting markets (spread, total & Money Line), best bets for spread, total, money line, and same game parlays. It also features prop bet probabilities for first & anytime touchdown scorer. Individual player projections for passing, rushing, receiving yards & touchdowns for betting and fantasy use.
- Buccaneers @ Lions
- 49ers @ Cardinals
- Dolphins @ Raiders
- Colts @ Steelers
- Falcons @ Chiefs
- Bears @ Jaguars
- Bengals @ Texans
- Giants @ Ravens
- Browns @ Jets
- Panthers @ Football Team
- Broncos @ Chargers
- Eagles @ Cowboys
- Rams @ Seahawks
- Titans @ Packers
- Bills @ Patriots
NFL Week 16 odds & betting lines
Get the latest NFL Week 16 odds and betting lines powered by BetMGM sportsbook.
Pickswise is the home of free NFL predictions. Check out the latest NFL props and NFL parlays as well as expert underdog predictions and computer picks.
