NFL Week 15 picks and predictions - Millionaire maker 14-team money line parlay at (+264142 odds): Lions keep rolling

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Caleb Wilfinger

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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.
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Week 15 of the 2022 NFL season is getting underway with Thursday Night Football between the San Francisco 49ers and Seattle Seahawks, but now it’s time to look ahead toward the weekend schedule. This slate features a sizable 14 games, with some massive playoff implications at hand. Each week we are choosing a millionaire parlay, picking every game on the money line for the chance at a massive payday.

Without further ado, here is our 14-leg Week 15 millionaire parlay. It would pay out at +264142 odds!

Make sure to check out our NFL Week 15 picks for EVERY matchup!

Minnesota Vikings ML (-198) over Indianapolis Colts

While the Vikings are undoubtedly overrated by the general sports media, Minnesota should still take care of business against a Colts team in free-fall.

Check out our full Colts vs Vikings predictions

Baltimore Ravens ML (+130) over Cleveland Browns 

It shouldn’t matter who suits up at quarterback for the Ravens. Baltimore is the better team and is a bit undervalued against a mediocre Browns side.

Check out our full Ravens vs Browns predictions

Buffalo Bills ML (-300) over Miami Dolphins

The Bills defense is trending up while the Dolphins offense is clearly trending down. This sets up nicely for Buffalo to clinch the AFC East at home.

Check out our full Dolphins vs Bills predictions

Detroit Lions (-105) ML over New York Jets

The Lions have a top 10 offense over the last 6 weeks and the Detroit defense has been better of late. The Jets defense is a different animal, but I have concerns about New York’s ability to play from behind with Mike White at quarterback.

Check out our full Lions vs Jets predictions

Atlanta Falcons ML (+172) over New Orleans Saints

Desmond Ridder is making his first career start for a Falcons team that is probably better than their record suggests. On the other hand, the Saints offense is miserable. Atlanta has a real shot to pull the upset on the road.

Check out our full Falcons vs Saints predictions

Kansas City Chiefs ML (-900) vs Houston Texans

This one doesn’t need to be talked about much. Kansas City should sleepwalk its way to another easy victory.

Check out our full Chiefs vs Texans predictions

Philadelphia Eagles ML (-400) vs Chicago Bears

The Eagles are closing in on a No. 1 seed in the NFC, while the Bears have significant injuries on both sides of the ball. Philadelphia should win comfortably.

Check out our full Eagles vs Bears predictions

Carolina Panthers ML (-152) over Pittsburgh Steelers

Don’t look now, but the Panthers are just 1 game out in the NFC South. Sam Darnold and company need this game, and I think they’ll do just enough to get a massive victory.

Check out our full Steelers vs Panthers predictions

Dallas Cowboys ML (-205) over Jacksonville Jaguars

This could be one of the best games of the weekend, with Jacksonville’s offense catching fire in recent weeks. Despite the clear improvements made by the Jaguars, I expect Dallas to squeak by with a victory.

Check out our full Cowboys vs Jaguars predictions

Arizona Cardinals ML (+126) over Denver Broncos

Both of these teams are an absolute mess. Arizona is the slightly better side to me on paper, so I’ll lean with the Cardinals here.

Check out our full Cardinals vs Broncos predictions

New England Patriots ML (-106) over Las Vegas Raiders

The coaching mismatch is clearly an advantage for the Patriots in this matchup, so it’s hard not to back New England in a game between evenly matched teams.

Check out our full Patriots vs Raiders predictions

Los Angeles Chargers ML (-152) over Tennessee Titans

The Chargers offense finally shined in last week’s win over the Dolphins. While Mike Vrabel lives for this situation, I don’t think Tennessee has the talent on offense to keep up.

Check out our full Titans vs Chargers predictions

Cincinnati Bengals ML (-198) over Tampa Bay Buccaneers

The Bengals are playing as well as anyone right now, while Tampa Bay couldn’t look worse against quality competition. Cincinnati should stay hot, even against a desperate Buccaneers team.

Check out our full Bengals vs Buccaneers predictions

New York Giants ML (+190) over Washington Commanders

The Commanders don’t have many quality wins of late. So while the Giants have been struggling, there is too much respect for Washington in the betting market.

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