NFL Thanksgiving Betting Guide 2023: Lions vs Packers, Commanders vs Cowboys & 49ers vs Seahawks picks, predictions, odds & best bets

Oct 8, 2023; Detroit, Michigan, USA; Detroit Lions defensive end Aidan Hutchinson (97) tries to fire up the crowd after sacking Carolina Panthers quarterback Bryce Young (9) in the third quarter at Ford Field. Mandatory Credit: Lon Horwedel-USA TODAY Sports
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Caleb Wilfinger

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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.
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Happy Thanksgiving gamblers! We’ve got a great NFL slate ahead of us, kicking off with the Green Bay Packers vs Detroit Lions in a crucial NFC North Clash, before shifting to the NFC East for a game between the Washington Commanders and Dallas Cowboys. To close out the evening, we head to the pacific northwest for a game between the San Francisco 49ers and Seattle Seahawks. 

Here at Pickswise, we have everything you need to bet better on Thanksgiving Day, including NFL picks on every side and total, expert NFL player prop bets from our props betting expert and also a Same Game Parlay for each of the games. Let’s get into our Thanksgiving Day betting guide. 

NFL Thanksgiving Day Picks

NFL Thanksgiving Day best player prop bets

NFL Thanksgiving Day Same Game Parlays

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