NFL Parlays

Get our best NFL parlays every week of the 2024-25 season. Our experts combine their best NFL bets to create the best NFL parlay picks this week. You can also find our NFL same game parlays from each game, all season long.

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Sunday's NFL Week 12 parlay
Today
Detroit Lions
Indianapolis Colts
DET Lions @ IND Colts · Point Spread
DET Lions -6.5
Our Analysis

The Detroit Lions will be looking to solidify their new status as Super Bowl favorites when they visit the Indianapolis Colts on Sunday afternoon. That’s right; the Detroit Lions are favored to win the Super Bowl. They assumed the top spot for the first time this season — and first time in franchise history — following this past week’s 52-6 humiliation of the Jacksonville Jaguars that coincided with the Kansas City Chiefs’ first loss. And it’s hard to argue with the odds. Detroit is an absolute wagon from an offensive standpoint. Jared Goff bounced back from his interception barrage in Week 10 by torching Jacksonville for 412 yards and 4 touchdowns on 25-of-29 passing. Amon-Ra St. Brown (2), David Montgomery (2) and Jahmyr Gibbs (1) scored at least 1 touchdown in the same game for the 8th time in their careers — already a record for 3 teammates in the history of the NFL.

Indianapolis +3.5 against the New York Jets was a 3-star best bet winner for me in Week 11, but I’m prepared to fade the Colts this time. After all, facing the Lions is the most opposite extreme you can possibly get compared to facing the Jets. Indy squandered all of a 13-0 lead over the Jets before recovering late, so that really doesn’t inspire much confidence. Jonathan Taylor averaging just 2.4 yards per carry in that game also isn’t encouraging. What’s even more worrying is that the Colts rank 26th in the league against the pass and 25th in opponents’ yards per pass attempt. How do you think they are going to stop Goff, St. Brown and the rest of the gang? I would be more than happy to play this at -7.5, which you can get at plus money (+100) at time of publishing. However, at less than a touchdown (and PAT) it evokes max confidence. The Lions should continue to roll.

Lions vs Colts prediction: Lions -6.5 (-120) available at time of publishing. Playable to -7.5 (+100).

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Dallas Cowboys
Washington Commanders
DAL Cowboys @ WAS Commanders · Point Spread
DAL Cowboys +10.0
Our Analysis

We have a classic rivalry showdown here in the NFC East this week as the Washington Commanders get ready to host the Dallas Cowboys. A couple years ago it would have sounded crazy to say the Commanders would be one of the toasts of the league while the Cowboys would be a laughingstock, but that’s where we’re at. Dallas is in free-fall in the wake of Dak Prescott’s injury and it is coming off a blowout loss at home to the Texans.

I think there is value in buying low on the Cowboys. We are getting them at their absolute rock-bottom price in the market after the spanking on national TV at the hands of Houston that everyone saw, but it’s important not to overreact. This is a division game that’s going to be hard-fought, and getting double-digits is too good of an opportunity to pass up. I also just think Washington is a bit overrated. The Commanders are 3-3 in their last 6, and that figure gets worse when you dig into it. Their 3 wins in that span? They have come against the Giants, Panthers and Bears. New York and Carolina might be the 2 worst teams in the league and Chicago hasn’t looked much better of late. And even the Bears they only beat on a last-second, walk-off Hail Mary.

Jayden Daniels has quietly come back down to Earth following his red-hot start, and over his last 2 games he has just 1 touchdown while averaging fewer than 6 yards per attempt. Even against the G-Men, the Commanders only managed to win by 5 in a game that came down to the wire after they almost choked to Daniel Jones. As such, I don’t see any reason to feel good about laying double-digits with them on Sunday. The Cowboys have also played much better on the road this year; they are 0-5 at home but 3-2 on the road.

Cowboys vs Commanders prediction: Cowboys +10 (-110) available at time of publishing. Playable at that number.

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Tennessee Titans
Houston Texans
TEN Titans @ HOU Texans · Point Spread
HOU Texans -8.0
Our Analysis

The Texans picked up a statement win in Week 11. Monday Night Football featured an in-state rivalry between the Texans and Cowboys that didn’t stay competitive for long. The game became a talent show for Joe Mixon, who finished with over 100 rushing yards and 3 touchdowns. His supporting cast of Nico Collins and Tank Dell didn’t need to do much since the game got out of hand by the second half. Houston’s dangerous duo will have a more difficult matchup in Week 12 against a Titans secondary that has allowed the fewest passing yards per game this season. However, Sam Darnold proved that you can still have success against the Titans’ defense as long as you spread the wealth. The Vikings beat the Titans by 10 last week and it was because Darnold completed a pass to 9 different receivers and took care of the ball. That’s likely going to be the game plan for CJ Stroud: utilize his talented group of receivers and don’t just rely on Collins.

The Tennessee offense has been a problem this season. In their last 6 games, the Titans have scored 13, 17, 20, 14, 10 and 17 points. The only time they reached 20 points has an asterisk next to it since it took them until overtime to reach that number. Regardless, you can see the trend. And it won’t get any easier for Will Levis on Sunday since the Texans are allowing the 6th-fewest passing yards per game this season. Houston limited the Cowboys to just 10 points in Week 11 and I wouldn’t be surprised if the Titans finish with a similar score. I’m envisioning a score ending around 30-14 in favor of the Texans, so back the home team to cover the spread.

Titans vs Texans prediction: Texans -8.0 (-110) available at time of publishing. Playable to -8.5.

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Sunday's NFL Week 12 mega parlay
Today
Denver Broncos
Las Vegas Raiders
DEN Broncos @ LV Raiders · Alternate Point Spread
DEN Broncos -9.5
Our Analysis

Bo Nix has shot up the rookie rankings in the last few weeks. Heisman winner Jayden Daniels was the talk of the rookie class in the first month or so, but Nix’s overall consistency is starting to get him recognized. He’s thrown for 1,029 yards, 9 touchdowns and just 1 interception in the last 4 weeks and gets a fortunate matchup against a terrible Raiders defense in Week 12. However, this won’t be the first time Nix has faced Las Vegas. Denver faced the Raiders back in Week 5 and the game turned one-sided very quickly. Nix threw for 206 yards and 2 touchdowns while rushing for another touchdown as the Broncos won 34-18. Since that loss, the Raiders are 0-5 and have lost by 19, 5, 7, 17 and 15 points. These teams are moving in opposite directions.

There are several different problems with the Raiders at the moment. Their quarterback situation is concerning, they lack offensive weapons since they traded away Davante Adams and their defense is allowing the 4th-most points per game. Las Vegas has allowed 34, 41, 27, 20, 32 and 34 points in the last 6 weeks. Expect Nix to take advantage of a sinking Raiders team and win by double digits.

San Francisco 49ers
Green Bay Packers
SF 49ers @ GB Packers · Alternate Point Spread
SF 49ers -2.5
Our Analysis

This is a great buy-low spot for the 49ers. San Francisco got Christian McCaffrey back 2 weeks ago and people expected him to be a catalyst of change for the Niners. But the Niners are 1-1 with CMC and their win came from a game-winning field goal against a Bucs squad without Mike Evans or Chris Godwin. I wasn’t too surprised to see them as underdogs for Week 12 in Green Bay considering their recent performances. With that said, the 49ers have still been playing well on offense. Brock Purdy has thrown for over 500 yards and 3 touchdowns in the last 2 weeks, Jauan Jennings has stepped into the role of an elite receiver, and CMC ran for 79 yards last week. It’s on the defense to step up and limit unnecessary penalties.

I’ll be honest — I’ve been disappointed in the Packers lately. That might sound crazy since Green Bay has won 5 of their last 6 games but hear me out. They barely beat a sinking Jags team 3 weeks ago, their offense was completely shut down by the Lions 2 weeks ago and they only beat the Bears last week because they blocked a game-winning field goal. Jordan Love has made a lot of mistakes lately and I think the Niners can capitalize on that and win this game by a field goal or more.

Philadelphia Eagles
Los Angeles Rams
PHI Eagles @ LA Rams · Point Spread
PHI Eagles -2.5
Our Analysis

The Eagles might be the hottest team in the NFL right now. Philly is on a 6-0 run with wins over the Commanders, Cowboys, Jaguars, Bengals, Giants and Browns. The wins haven’t been small either, considering the Eagles scored at least 26 points in 5 of those games. The offense is finally healthy and is looking incredibly dangerous right now with AJ Brown, DeVonta Smith and Dallas Goedert as Jalen Hurts’ top options with Offensive Player of the Year frontrunner Saquon Barkley in the backfield. Philly will take on a Rams defense that has allowed the 11th-most points per game this season and has struggled in the secondary. L.A. just surrendered 282 yards and 2 touchdowns to Drake Maye and the Patriots last week.

These teams might go punch-for-punch on offense since the Rams have just as many elite weapons. Puka Nacua and Cooper Kupp might be the best wide receiver duo in football right now and Kyren Williams has been a more than serviceable back. Plus, Matthew Stafford has turned back the clock this season. The 36-year-old has thrown 10 total touchdowns and at least 275 passing yards in each game in the last 4 weeks. However, this will be his toughest test yet. The new and improved Philly secondary is allowing the 2nd-fewest passing yards per game this season. And the Rams won’t have too much success if they turn to Williams on the ground since the Eagles’ defensive line has allowed the 7th-fewest rushing yards per game. I’m taking Philadelphia to win this one by at least a field goal to wrap up my NFL parlay picks.

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NFL Video

What Is An NFL Parlay

An NFL parlay is a type of bet where you combine multiple selections into a single wager. For an NFL parlay to win, all of the selections or bets need to win. While the difficulty of winning an NFL parlay increases with each selection you add, the odds can also greatly increase. To calculate the odds of a parlay you multiply the odds of the individual selections so the more selections, the bigger the parlay odds. You can also make use of our Parlay Calculator to take care of all of the math for you. For more on Parlays be sure to check out our Parlay betting guide.


Our experts will highlight the best NFL Picks today to combine into an NFL Parlay, offering you even more variation into how you want to wager on this week’s NFL action.

Free Picks and Parlays NFL 

Here at Pickswise, we have free NFL picks and parlays every week of the NFL season. Our free NFL parlays include both traditional multi-game parlays which include our best parlay picks from the most popular markets including money line, spreads, and totals, as well as our NFL Same Game parlays. Each of our free NFL parlays will come with a full analysis for each leg, as well as the best odds available from all of the top online sportsbooks. Check back every week including for those primetime parlay picks on Mondays, Thursdays, and Sunday Night Football.

NFL Parlay Strategies & Tips

Parlay Bets despite their popularity can be one of the most difficult and lucrative bets, with increased difficulty with each selection you add. It’s important to remember that over the course of the NFL season even experts will very likely lose more parlays than they win. However, the nature of parlay betting means the wins you do get turns more profit.

In the 2023-24 NFL season our expert handicappers landed 38.5 units of profit from parlays, so you need to look no further for a trusted source of NFL parlay picks.


Here are three quick tips to better your chances of winning long-term with your NFL Parlays

  1. Stick to 2, 3, or 4 team parlays – Any more than this will often not be profitable long term despite the increased parlay odds. 
  2. Shop around for odds – Not all online sportsbooks offer the same odds, and while there is often only a marginal difference if you can wager three picks at -105 each instead of -120, your payout would be $744.21 instead of $616.20 to a $100 stake.
  3. Manage your bankroll –  Being disciplined with your bankroll is key long term as not all parlays will win, particularly in the NFL, but if you keep your stake consistent, at odds of around 6/1, you only need to win 1 in 7 parlays to break even, any better than that is profit.

How to bet on NFL Picks and Parlays

Betting on NFL picks and parlays is a quick and simple process with any online sportsbook. To create a parlay, you simply have to add multiple selections to your bet slip and click the parlay option before placing your wager.

Due to the popularity of NFL betting and also NFL parlays, sportsbooks pay a considerable amount of attention to these markets, and in shopping around you can find great variations in odds, spread lines, and often price boosts or bonuses such as Parlay insurance whereby you get your stake as a bonus bet if only one leg lets you down. Shopping around for these advantages is key to having long-term success with NFL parlays.

Unsure where is best to place your NFL parlay bets? Head over to our
online sportsbook promotions page where we break down all the information and latest promo codes you’ll need to know to unlock bonuses and make your NFL betting easier.

What is an NFL Teaser Bet?

One of the ways to avoid the frustration of losing an against-the-spread bet by a point or two is with teaser NFL picks. For example, in a 2-team teaser, you get 6 points placed in your direction (-7 spread becomes -1) for both games. The caveat is that both teams must cover for your ticket to be graded a winner and the odds are similar to a single-game bet. Conversely in a parlay, you still wager on two teams but with the original spread and with better payout odds (usually 3:1). Teasers and parlays can be played with 2,3,4,5 teams or more.

What Is A Same Game Parlay 

A Same Game Parlay is just like a regular parlay wager, except all selections come from prop bets within one specific game. The obvious positive of a Same Game Parlay is that by combining multiple selections you can go for an even bigger win with the odds increasing with each selection.

Bettors will often use Same Game Parlays to wager on correlated props, and if you get it right the payouts can be huge. Take, for example, a team facing a poor pass defense with an elite QB, in that spot, you might take the QB to hit over their passing yards total and you can also parlay that with their favorite wide receiver to score anytime and the team to win.

How Do I Bet On A Same Game Parlay

With the Same Game Parlay’s increasing popularity, the majority of leading online sportsbooks now offer them across a number of sports, including the NFL. Some refer to them as One Game Parlays and Single Game Parlays, which are different in name, but the same in concept.

To bet on a same game parlay simply head to your preferred online Sportsbook, or where you can get the best odds for your picks. Unsure of the best online sportsbook for the NFL? Check out our guide to the best NFL betting sites today.

To bet a Same Game Parlay you must first click on the game you want to place a bet on, and then add each selection to your betslip. The Same Game Parlay odds update with each pick. Once you have added all of your selections, enter the amount you wish to wager and hit ‘place bet’. And that’s it, you’re on!

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NFL Parlays: Betting small to try to win big

Bet small, win big. That’s the aim of every NFL parlay and our team of experts spend hours each week crafting what they believe to be the perfect parlay to deliver a nice payout. Our handicappers are among the best in the business at doing just that, with each leg the product of intensive analysis from numerous members of the Pickswise capping team. Our record speaks for itself when it comes to NFL parlay expertise, throughout the 2023 season our NFL parlays had scored 38.5 units in profit.

Andrew Wilsher, Pickswise Managing Editor

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NFL Parlays FAQs

You cannot parlay NFL Win Totals bets as the outcomes of the events are closely correlated. If you were to bet the Overs on the Saints, but the Unders on the Buccaneers for example, and the Saints beat the Bucs twice in a season, both outcomes are likely to increase their chances of winning.

A parlay bet in the NFL is when you combine multiple straight bets into one single bet. Every pick within the parlay must win for the ticket to cash, but the odds also increase in line with the risk of adding more picks, making them fruitful if they hit. 

You can parlay certain NFL futures before and during the season, but it will vary from sportsbook to sportsbook. One example would be division winners, you can try to hit a big parlay and predict all 8 division winners in a season. Some sportsbooks will also allow you to parlay Player Awards such as Offensive and Defensive Rookie of The Year.

Parlays can be worth it, but it’s also worth keeping in mind that the more picks you have in a parlay the harder it will be to win. However, with the odds of each individual pick multiplying to give you the parlay odds, it allows you to bet smaller units to try and win bigger returns than a straight wager.

The disadvantage of a parlay is its difficulty to win. While the odds are often great, adding each pick will also increase the risk of the bet winning as every selection has to win for the ticket to cash, a single losing leg with 5 winning ones still returns $0.

Parlays are popular because they offer the opportunity of betting small and win big. For example, if you were to parlay 6 teams against the spread, you should expect odds of around +4500 meaning a $50 bet would return $2,300.

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