NFL betting guide: Expert Week 6 NFL predictions, picks, odds & best bets

Detroit Lions tight end Sam LaPorta (87) takes the field for the game against Denver Broncos at Ford Field in Detroit on Saturday, Dec. 16, 2023.
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Caleb Wilfinger

NFL

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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.
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Welcome to the Pickswise NFL Week 6 betting guide! On the heels of an exciting first 5 weeks, we’ve got another terrific weekend of football in store for us, headlined by a couple of marquee matchups in Lions vs Cowboys & Bills vs Jets.

What’s in store for Sunday? Well, our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL weekend. You can also read our great NFL predictions for every game on the Week 6 slate of the NFL regular season.

 

NFL Week 6 picks 

NFL Week 6 expert betting picks and predictions 

NFL Week 6 prop bets 

NFL Week 6 big-game predictions 

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