NFL betting guide: Expert Week 15 NFL predictions, picks, odds & best bets

Welcome to the Pickswise NFL Week 15 betting guide! On the heels of an exciting first 14 weeks, we’ve got a massive slate of football in store for us, headlined by a trio of marquee matchups in Steelers vs Eagles, Bills vs Lions and Packers vs Seahawks. 

What’s in store for Sunday? Well, our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL weekend. You can also read our great NFL predictions for every game on the Week 15 slate of the NFL regular season. 

NFL Week 15 picks 

• NFL picks against the spread and total for EVERY Week 15 game 
• NFL best bets  
• NFL parlays 

NFL Week 15 expert betting parlay picks and predictions 

• NFL expert best bets
• NFL Sunday mega parlay (+1022 odds!)
• NFL SNF Same Game Parlay

NFL Week 15 prop bets 

• NFL Week 15 SNF prop bets
• NFL Week 15 prop bets
• Week 15 SNF touchdown scorer best bets 

NFL Week 15 big-game predictions 

• Dolphins vs Texans predictions 
• Steelers vs Eagles predictions
• Bills vs Lions predictions
• Colts vs Broncos predictions
• Buccaneers vs Chargers predictions
• Packers vs Seahawks predictions