NFL betting guide: Expert Week 10 NFL predictions, picks, odds & best bets

San Francisco 49ers running back Christian McCaffrey (23) celebrates a touchdown against the Arizona Cardinals during the first half at State Farm Stadium.
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Caleb Wilfinger

NFL

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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.
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Welcome to the Pickswise NFL Week 10 betting guide! On the heels of an exciting first 9 weeks, we’ve got another terrific weekend of football in store for us, headlined by a couple of marquee matchups in Lions vs Texans and Steelers vs Commanders.  

What’s in store for Sunday? Well, our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL weekend. You can also read our great NFL predictions for every game on the Week 10 slate of the NFL regular season. 

 

NFL Week 10 picks 

NFL Week 10 expert betting picks and predictions 

NFL Week 10 prop bets 

NFL Week 10 big-game predictions 

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