NFL betting guide: Expert 2022 Week 10 NFL picks, predictions, odds & best bets

Deebo Samuel races away to the end zone in the 49ers Week One win at the Detroit Lions same game parlay
Photo of Ricky Dimon

Ricky Dimon

NFL

Show Bio

Since graduating from Davidson (The College That Stephen Curry Built), I have been writing about sports -- just about any and all you can think of! -- and coaching tennis in Atlanta, GA. Beyond the four major sports, I am an avid tennis fan and cover the ATP Tour on a daily basis. If I'm not busy writing, you can generally find me on a tennis court or traveling the world wherever a sporting event takes me. For Ricky Dimon media enquiries, please email contact@pickswise.com.
Read more about Ricky Dimon

Welcome to the Pickswise NFL Week 10 betting guide! The week got off to a thoroughly unspectacular start with a boring Thursday Night Football contest between the Carolina Panthers and Atlanta Falcons, but that is nothing new for TNF this season. That should not be a sign of things to come for the rest of the Week 10 slate.

Sunday should begin with a bang, as the Tampa Bay Buccaneers need a second straight victory in the worst way but have to go up against the NFC West-leading Seattle Seahawks. That showdown will be the first NFL game played in Germany and gives the Sunday slate an early start at 9:30am ET. Meanwhile, Buffalo Bills are hosting the Minnesota Vikings and Dallas Cowboys head coach Mike McCarthy returns to Lambeau Field for a date with the Green Bay Packers.

Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL Sunday – and for Commanders vs Eagles on Monday Night Football. Don’t forget to check out our NFL game previews, which now include prop picks, projections, trends and Same Game Parlays.

Our handicappers engineered a stellar first half of the 2022 season, as we are 34-20 on our best bets. Let’s keep the momentum going!

NFL Week 10 picks

NFL Week 10 expert betting picks and predictions

NFL Week 10 prop bets

NFL Week 10 Promo Codes

Find all the latest Sportsbook Promo Codes and Bonuses for NFL Week 10, including sportsbooks live in your state.

NFL Week 10 big-game predictions

Watch Pickswise Playbook!

Our weekly NFL preview show Pickswise Playbook, presented by Superbook Sports, is hosted by Lauren Jbara and Jared Smith with special guest Tank Williams.

Pickswise is the home of free NFL Picks and NFL Odds. Check out the latest NFL Prop Bets and NFL Parlays as well as expert NFL Underdog Picks and NFL Computer Picks.

Pickswise
*
By signing up you agree to our terms and privacy policy