NFL betting guide: Conference championship NFL picks, predictions, odds & best bets

Dec 4, 2022; Cincinnati, Ohio, USA; Kansas City Chiefs quarterback Patrick Mahomes (15) leaps into the end zone for a touchdown in the third quarter of a Week 13 NFL game against the Cincinnati Bengals at Paycor Stadium. Mandatory Credit: Kareem Elgazzar-USA TODAY Sports
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Phil Agius

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I've been writing about the NFL and a host of other sports for the UK's top daily betting paper the Racing Post for more than 20 years. An incurable Browns fan (1-31 survivor), I also specialise in all kinds of motorsport betting including F1, MotoGP, IndyCar and NASCAR. For Phil Agius media enquiries, please email contact@pickswise.com.
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Welcome to the Pickswise NFL Conference Championship betting guide! The race to win the Vince Lombardi Trophy is in sharp focus now with each conference fielding heavyweight contenders in Sunday’s Super Bowl or bust showdowns.

In the AFC, we have a rematch of last season’s game between defending conference champions the Cincinnati Bengals and the Kansas City Chiefs (6:30pm ET, CBS). The Chiefs have reached this stage for an incredible 5th straight year. They have a 2-2 record in those games after the 27-24  loss to the Bengals last year, and all eyes are on Chiefs QB Patrick Mahomes, who picked up an ankle injury in last week’s win over the Jaguars. The Bengals won by the same score in the teams’ regular-season meeting and have won their last 3 games against KC, although Andy Reid’s team held a sizeable lead in each of those games.

The NFC representative in the Super Bowl will be known earlier on Sunday evening as the 49ers take on the Eagles at Lincoln Financial Field (3:oopm ET, FOX). The Eagles were the dominant force in the conference for much of the first half of the season, but the 49ers came on strong in the second half of the year after acquiring RB Christian McCaffrey and with rookie QB Brock Purdy impressing everyone with his poise.

The 49ers reached this stage last season, losing 20-17 to eventual Super Bowl winners the Los Angeles Rams, while the Eagles were most recently in this game 5 years ago, beating the Vikings 38-7 on their way to a Super Bowl success.

Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL weekend. You can also read our great NFL predictions for both games or follow the links to all the individual analysis and picks below.

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NFL Conference Championship picks

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NFL Conference Championship predictions

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