College football betting guide: Expert Week 6 CFB predictions, picks, odds & best bets

Ohio State Buckeyes celebrate with fans after defeating Michigan State Spartans at Spartan Stadium on Saturday.
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Andrew Wilsher

NCAAF

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Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email contact@pickswise.com.
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We’re approaching the midway point of the 2024 college football season as we’ve reach Week 6 and have another huge batch of great matchups to get excited for. Here at Pickswise, our team of expert CFB handicappers have EVERY big game covered for Saturday’s mega slate, and you can find out all of our college football picks and CFB predictions for those matchups. On top of that, we have our top experts’ best bets of the day, along with our parlays and Same Game Parlay picks to help you bet better today across all of the NCAAF action. Let’s dive in!

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College football Week 6 best bets

Our top college football expert gives their best bets across Saturday’s huge slate.

College football Week 6 parlays

See our CFB Week 6 parlay for Saturday’s games, while we have an SGPs for the big conference matchup between the Iowa Hawkeyes and Ohio State Buckeyes.

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College football Week 6 picks

Below, you’ll find our betting previews and NCAAF predictions for the hottest matchups in Week 6:

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