College football betting guide: Expert Week 10 CFB predictions, picks, odds & best bets

Ohio State won the most recent meeting against Penn State, 20-12, at Ohio State in Columbus on Oct. 21, 2023.
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Andrew Wilsher

NCAAF

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Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email contact@pickswise.com.
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We’ve reached November and we’re now officially into the final month of the 2024 college football regular season. With that in mind, the stakes continue to get higher, especially as teams begin to scramble in their bid to reach the 12-team College Football Playoff. Among those are Ohio State and Penn State, who meet at 12:00 pm ET on Saturday with the Nittany Lions putting their undefeated streak on the line. Both teams are currently ranked in the top 4 but a defeat could have a lasting impact. Meanwhile, #1 Oregon makes the trip to Michigan to take on the reigning national champion Wolverines while Georgia hosts Florida.

You can find all of our college football picks and CFB predictions for Saturday’s big matchups. On top of that, we have our college football expert’s best bets of the day, along with our parlays and Same Game Parlay picks to help you bet better today across all of the NCAAF action. Let’s dive in!

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College football Week 10 best bets

Our top college football expert gives their best bets across Saturday’s huge slate.

College football Week 10 parlays

Lock in our CFB Week 10 parlay for Saturday’s games, while we also have an SGP for the huge Big Ten clash between the Buckeyes and the Nittany Lions.

We recommend using Bet365 if you’re looking to bet on our Ohio State vs Penn State Same Game Parlay, where you’ll find the best odds available. Not got a Bet365 account? No problem! Simply click here to join and you’ll INSTANTLY receive $200 in bonus bets when you make a first bet of just $5!

College football Week 10 picks

Below, you’ll find our betting previews and NCAAF predictions for the hottest matchups in Week 8. You can also check out our college football picks for EVEN MORE predictions.

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