Aaron Ashley
The 2024-25 UEFA Champions League quarterfinals conclude today as the 2nd legs wrap up and by 6:00 pm ET we should know all 4 semifinalists. Up first we have Inter Milan vs Bayern Munich, with the Italians holding a 2-1 advantage as they now welcome the German giants to the San Siro. Meanwhile, reigning champs Real Madrid have a mountain to climb after they lost their 1st leg 3-0 to Arsenal. Can the Spanish club turn things around or will Arsenal advance to the semis? Let’s break down each of our expert Champions League best bets for both quarterfinal games on Wednesday, while you can also find out our soccer predictions for more Champions League picks, along with our EPL and MLS best bets each week.
Inter Milan vs Bayern Munich best bet: Inter Milan ML (+165)
Inter Milan won 2-1 in Munich last week, putting them in a strong position going into Wednesday’s 2nd leg against Bayern. The Italian champions are still in the running for a treble this season, strengthened by back-to-back victories over the last 7 days. Inter fell short in Europe last season but they’re looking dangerous in this season’s Champions League. They’ve got an impressive defensive record and they’ve made their home ground a fortress, which leaves Bayern in a difficult spot as they look to turn this tie around.
It’s easy to assume that the Italian side will look to hold firm and protect their aggregate lead, but Inter could be more ruthless here. The hosts are aiming to continue a fantastic record at their own ground, having failed to win only 4 of 23 home games across all competitions this term. Inter have won all 5 home games in the Champions League this season, overcoming Arsenal, RB Leipzig and Feyenoord. They’ve won 12 of their previous 14 home games in this competition, including 9 of their last 10.
While Bayern are aiming to get back into this tie, they’ve lost half of their road trips in the Champions League this season. They’ve been beaten at Aston Villa, Barcelona and Feyenoord. That record makes the German side look vulnerable, despite entering this clash as slight favourites. With all this in mind, Inter Milan hold the value to win this 2nd leg and advance to the Champions League semifinals.
Read our full Inter Milan vs Bayern Munich prediction
Real Madrid vs Arsenal best bet: Both teams to score (-168)
Arsenal scored 3 2nd-half goals to secure a 3-0 1st-leg lead over Real Madrid in the Champions League quarterfinals last week, and more fireworks are expected when the 2 meet at the Bernabeu Stadium on Wednesday. Declan Rice’s stunning pair of free kicks set the Gunners on their way before Mikel Merino completed the scoring, leaving Los Blancos with a mountain to climb if their Champions League defense is to continue.
What we can expect on Wednesday is both teams to have plenty of attacking opportunities, with the hosts needing to go on the front foot early in an attempt to reduce the first-leg deficit and change the complexion of the tie. However, that could leave Real Madrid vulnerable in defense, and shutouts have been hard to come by at the Bernabeu lately. Both teams have scored in 10 of their last 11 competitive games here, and Arsenal’s last 3 on the road have featured goals at both ends, making that a standout pick for Wednesday.
Read our full Real Madrid vs Arsenal prediction
