Even though next week will decide the #1 seed in the NFC and NFC North, Lions vs 49ers comes to us tonight on MNF to close out Week 17, with Detroit coming in as road favorites. Let’s get into our Lions vs 49ers touchdown scorer best bets for Monday Night Football, while you can also find out our NFL picks on the side and total for this matchup and EVERY game throughout the 2024 season.
Read our full Detroit Lions vs San Francisco 49ers predictions for MNF
Lions vs 49ers anytime touchdown scorer pick: Jameson Williams (+200)
Odds available at Bet365 at time of publishing.
We’ve written about Jameson Williams more times than we can count. With the Lions being on primetime on what feels like every other week, Williams tends to regularly find himself on our anytime touchdown scorer articles, and he’s here once again. Williams is averaging 19 yards per reception and is tied for 1st in 50+ yard receptions. We saw one last week where Williams took an 82-yard catch to the house against the woeful Chicago Bears. He ended the game with 143 yards — the most of his young career. With no David Montgomery, a Jahymr Gibbs touchdown price of -230 and a ton of attention on Amon-Ra St. Brown, Williams is an excellent bet at +175 to find the end zone against a 49ers defense that has allowed 25+ points in 3 of their last 5 games.
Check out our best Lions vs 49ers player prop bet, with our props experts currently on a 10-3 run!
Lions vs 49ers anytime touchdown scorer pick: Sam LaPorta (+195)
Odds available at FanDuel Sportsbook at time of publishing
Most of the time, it’s best to back the team with an implied team total of 27 points on primetime. That’s the Detroit Lions. As spoken above, we’re not laying the -230 price on Gibbs to score. Meanwhile, St. Brown is a safe bet, but getting Sam LaPorta at near 2/1 odds is more appealing. After a slow start to his sophomore campaign that resulted in zero touchdowns in his first 4 games, LaPorta and Jared Goff are building their connection back up. Over the last 5 games, LaPorta ranks just behind David Njoku in red-zone targets amongst tight ends. During that span, he’s scored 3 times, with 2 of those touchdowns coming in the red zone. Expect continued fireworks from the Lions’ offense, led by Jared Goff, who has a passing touchdown line of over 1.5 TDs priced at -205 on DraftKings.
Find out our Lions vs 49ers Same Game Parlay picks for MNF at +632 odds