The first Grand Slam of the 2025 tennis season is already upon us, as the Australian Open gets underway at Melbourne Park on Sunday. Novak Djokovic, the only member of the “Big 3” still on tour, is a 10-time champion Down Under but relinquished the Aussie throne to Jannik Sinner last year. Does Djokovic have at least 1 more title in him, or will Sinner and Carlos Alcaraz continue a changing of the guard? Meanwhile, second-ranked Alexander Zverev looks poised to finally become a major champion after playing brilliantly throughout the 2024 campaign. Let’s take a look at the odds and Australian Open best bets to make for the men’s singles competition in Melbourne.
You can also find out our Australian Open women’s singles winner predictions, which includes a +5000 longshot
Australian Open tennis men’s singles odds
Odds courtesy of DraftKings Sportsbook and available at time of publishing.
- Jannik Sinner +150
- Carlos Alcaraz +320
- Novak Djokovic +450
- Alexander Zverev +1000
- Daniil Medvedev +1600
- Taylor Fritz +2800
- Stefanos Tsitsipas +4000
- Holger Rune +5000
- Alex de Minaur +5000
- Jack Draper +5000
- Andrey Rublev +6500
- Hubert Hurkacz +6500
- Giovanni Mpetshi Perricard +6500
- Arthur Fils +6500
- Nick Kyrgios +6500
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Australian Open tennis best bet: Jannik Sinner (+150)
Sinner could not have asked for a better draw for his title defense. The world No. 1 is on the opposite side from both Alcaraz and Djokovic, who could go head-to-head as early as the quarterfinals. Zverev could face the Alcaraz-Djokovic winner in the semis. Sinner’s potential path includes a fourth-round date with either Holger Rune or Hubert Hurkacz and a quarterfinal contest against either 2022 and 2024 Australian Open runner-up Daniil Medvedev or 2024 U.S. Open runner-up Taylor Fritz. You have to like everything about Sinner right now. Not only is he the defending champion Down Under, but his late-season stretch in 2024 featured titles at the US Open and Nitto ATP Finals.
Australian Open tennis prediction: Daniil Medvedev (+1600)
It’s been a long time since you could get Medvedev at this kind of odds to win a Grand Slam (not including the French Open, where he always has long odds due to his disdain for clay). The Russian is a relative longshot this year since he went all of last season without winning a single tournament. Still, it’s not like Medvedev played poorly. He is still ranked a solid #5 in the world and he came within 1 set of winning the Aussie Open (lost to Sinner in 5 sets after leading 2 sets to love). Having already played in 2 finals at Melbourne Park, there is no reason why Medvedev can’t go 1 step farther this time around. Being in Fritz’s quarter of the bracket improves the 28-year-old’s chances to an even greater extent.
Australian Open tennis longshot pick: Tommy Paul (+10000)
Although the Australian Open has not produced a whole bunch of unexpected champions over the years, there have been more than enough surprising results such that you never know when a longshot winner is going to emerge. Lower-ranked semifinalists and even finalists are often the norm Down Under. If someone from outside the top 10 is poised to go all the way this year, it could be Tommy Paul. The 27-year-old is a former semifinalist in Melbourne (2023) and a brilliant 2024 campaign from start to finish propelled him to #12 in the rankings. Paul finds himself in a favorable spot as part of the Zverev-Casper Ruud section of the draw, and he very well might take advantage.