2025 NFL Draft Betting Guide: Expert NFL Draft Predictions, Best Bets & Picks

Flags promoting the 2025 NFL Draft pictured on April 19, 2025, at Leicht Memorial Park in Green Bay, Wisconsin.
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Andrew Wilsher

NFL

Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email contact@pickswise.com.
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Ladies and gentlemen, welcome to the 2025 NFL Draft! One of the most exciting weeks in the football calendar is upon us, and while the #1 pick is almost a lock at this point (Cam Ward to the Titans is currently -10000), there’s sure to be a ton of chaos that follows with plenty of superstars waiting in the wings and lots of teams rumored to be signing Colorado QB Shedeur Sanders. We also have a stacked group of offensive linemen and cornerbacks in the mix. On top of that, rumors have been rampant around teams trading up, so it’s sure to be a memorable night. Our NFL experts have scoured the odds boards and have picked out their best bets, and even created a full first-round NFL mock draft! Let’s dive in.

2025 NFL Draft best bets and predictions

Pickswise’s 2025 NFL mock draft

  • Don’t miss our expert’s 2025 NFL mock draft, featuring picks for the ENTIRE first round to help with your betting picks on Thursday night!
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