Andrew Wilsher
Ladies and gentlemen, welcome to the 2025 MLB season! On Thursday, March 27, Opening Day will be upon us and so too will a 162-game odyssey for every MLB team through the spring and summer as we crawl our way to the postseason and, eventually, the 2025 World Series. The Dodgers justified favoritism last season to claim the 2024 World Series in a 4-1 sweep over the Yankees, and since then have reloaded and already started the new season 2-0 after sweeping the Cubs in Tokyo, Japan. Can Los Angeles become the first team since the 1998-2000 Yankees to go back-to-back? Here at Pickswise, we’ve pieced together our best MLB futures picks and have them available for you right here in our betting guide.
Let’s break down the latest World Series odds and our MLB futures picks, while you can also get our MLB picks on all the big games throughout the season. Make sure you don’t miss our MLB best bets either after our experts went 141-115-4 in 2023 and 69-59 in 2024.
2025 MLB World Series odds
Odds courtesy of Bet365 and available at time of publishing.
- Los Angeles Dodgers +225
- Atlanta Braves +900
- New York Yankees +900
- New York Mets +1000
- Philadelphia Phillies +1200
- Baltimore Orioles +1400
- Houston Astros +1800
- Boston Red Sox +1800
- Texas Rangers +2200
- Detroit Tigers +2800
- Arizona Diamondbacks +3000
- Chicago Cubs +3000
- Seattle Mariners +3000
- Cleveland Guardians +3000
- San Diego Padres +3300
- Kansas City Royals +3500
- Minnesota Twins +4000
- Milwaukee Brewers +4500
- Toronto Blue Jays +4500
- Tampa Bay Rays +6000
- Cincinnati Reds +7000
- Pittsburgh Pirates +10000
- San Francisco Giants +10000
- St. Louis Cardinals +12500
- Los Angeles Angels +15000
- The Athletics +15000
- Washington Nationals +25000
- Chicago White Sox +50000
- Colorado Rockies +50000
- Miami Marlins +50000
You can bet on the World Series winner and EVERY MLB game in the 2025 season with Bet365. And if you’re new to Bet365, even better! New users can click here now to join and they’ll receive $150 in bonus bets INSTANTLY when they make their first $5 bet!
2025 MLB futures picks
- 2025 MLB World Series predictions — find out our expert’s picks to win it all this season at +300 and +2500 odds!
- MLB Division Winner best bets — odds and our expert’s predictions for EVERY division winner this season, including one pick at +650 odds!
- MLB Win Total predictions — see which way our expert is going in their over/under win total best bets, targeting the Diamondbacks, Marlins and Red Sox
- MLB Player Award best bets — we have our picks on who will win the MVP, Cy Young and Rookie of the Year awards, including a couple of predictions at +1400
