Andrew Wilsher
Ladies and gentlemen, welcome to the 2025 college football season! It’s been over 7 months since Ohio State won the National Championship Game against Notre Dame and we’re now back in action with teams across the nation vying to reach the 12-team College Football Playoff. Here at Pickswise, we’ve got everything you need to bet better this season as our experts have looked through all the major college football futures markets to come up with their college football predictions and CFB best bets. You can also check out the latest NCAAF odds for futures and Week 1.
Below you can find links to all of our CFB picks so far for the 2025 season, but make sure you keep checking back as this page is updated daily with brand new college football futures content!
CFB National Championship predictions and best bets
- NCAAF National Championship predictions – find out our +480 best bet and longshot pick at +4000 odds!
College Football Heisman Trophy best bets
- Heisman Trophy odds and best bets — see our expert’s pair of predictions, including one at +6000!
College Football Conference previews and predictions
- SEC Championship predictions and betting analysis — can Arch Manning lead Texas to glory?
- ACC Championship picks and analysis — can this +1400 prediction shock Clemson?
- Big Ten Conference analysis and best bets — will it be Ohio State or Penn State?
- Big 12 Conference predictions and odds — find out our +800 pick to win the conference
- Sun Belt Conference odds and betting analysis — see our expert’s full breakdown of the SBC and best bet
- MAC best bets and contender breakdown — can Toledo justify favoritism?
