Houston Astros vs Minnesota Twins Prediction, Odds and Picks for Saturday, 04/05/25

After the Houston Astros took the opening game of the series with a 5-2 win on Thursday, the Minnesota Twins are looking to even things up on Saturday afternoon. Both of these teams are off to relatively cold starts, as the Astros enter this matchup with a record of 3-4, while the Twins are 2-5. The slow start for both teams can be mainly attributed to sub-par offensive production. In terms of total runs scored so far this season, the Twins and Astros are tied for 28th in the league with 41.

Houston starter Spencer Arrighetti impressed in his first start of 2025 last week, as he held the Mets to just one hit and one run over 6 innings of work. Minnesota starter Bailey Ober wasn’t nearly as impressive, as he lasted just 2.2 innings against the Cardinals. Ober has posted a WHIP under 1.08 over the past 3 seasons, and he should be able to get back on track against a Houston offense that hasn’t been setting the world on fire so far this season. It’s also worth noting that both bullpens will be well-rested after an off day on Friday. Look to the Under in this one.

Astros vs Twins prediction: Under 7.5 (-105) available at time of publishing. Playable to -110.

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