Houston Astros vs Kansas City Royals Prediction, Odds and Picks for Today, 04/25/25

The Houston Astros and Kansas City Royals begin a 3-game weekend series at Kauffman Stadium on Friday night. Houston hits the road after a 6-game home-stand, while Kansas City will be playing its fourth straight home game. The pitching matchup for Friday night will pit Houston’s Hayden Wesneski against Kansas City’s Seth Lugo. Wesneski has been a solid addition to the Houston rotation, as he has allowed just 16 hits in 23.0 innings of work so far this year. Lugo was one of the best pitchers in baseball a season ago, and he is off to a formidable start so far in 2025.

Both pitchers will face offenses that are off to slow starts. The Astros rank 23rd and the Royals rank 27th in total runs this season, and neither team is hitting many home runs. Kansas City is dead last in the majors with just 12 homers, and Houston’s 19 longballs rank 24th. It’s also worth mentioning that the Royals played a double-header on Thursday, so perhaps their offensive rhythm is thrown off for this one. All in all, consider the under.

Astros vs Royals prediction: Under 8 (-115) available at time of publishing. Playable to -120.

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