Detroit Tigers vs Baltimore Orioles Prediction, Odds and Picks for Today, 04/26/25

The Baltimore Orioles and Detroit Tigers open a 3-game weekend series at Comerica Park on Saturday afternoon. Saturday will feature a double-header between the 2 teams, as Friday’s contest was rained out. The first game of the afternoon could be a high-scoring affair. Baltimore owns the highest team ERA in the league at 5.25, and opponents are hitting a strong .291 against them. Brandon Young will be making his second career start in this one; his first one did not go well. The 25-year-old right-hander allowed 7 hits and 3 runs over 4.0 innings of work against the Reds. This will be his first career road start, and the Tigers’ offense should be ready.

Baltimore has relied on its offense a little too much, but the O’s are a strong offensive team that is capable of doing damage. They don’t strike out a lot, as they rank in the bottom third of MLB in total strikeouts at the plate. Casey Mize doesn’t rack up the strikeouts on the mound, so if Baltimore gets in good counts, they could get to Mize. It’s also worth mentioning that the nature of the double-header could handcuff each manager into saving some bullpen matchups for the second game. Consider the over.

Orioles vs Tigers prediction: Over 8.5 (-115) available at time of publishing. Playable to -125.

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