Cincinnati Reds vs Colorado Rockies Prediction, Odds and Picks for Today, 04/25/25

The Cincinnati Reds are in Colorado to take on the Rockies for a 3-game weekend series at Coors Field. The Rockies return home after wrapping up a road series at Kansas City on Thursday, while the Reds enjoyed an off day on Thursday. Cincinnati enters this matchup having won 9 of the last 10 meetings between these 2 teams, and they could have the edge in this one. Left-hander Andrew Abbott will take the mound for Cincinnati; he is off to a strong start with wins in each of his first 2 starts of the season. He has allowed just 4 hits and 2 earned runs over 11 innings and will face a Colorado offense that ranks last in the NL with a .213 batting average and .632 OPS.

Not much has gone right for the Rockies so far in 2025. They enter Friday’s contest with the worst record in baseball at 4-20 and have dropped 11 of their last 12 games. The projected starting pitcher for Colorado is Kyle Freeland, who left his last start after just 2.0 innings with a blister issue on his left hand. Prior to that start he had allowed 10 earned runs over his previous 2 outings. Run support has been tough to come by for the veteran lefty, as the Rockies have managed to score just 6 total runs in his 5 starts this season. Coming off an off day, consider backing the Reds.

Reds vs Rockies prediction: Cincinnati ML (-140) available at time of publishing. Playable to -145.

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